The longest-used assay depends on ingredients from ... This binding changes factor C’s shape and activates its protease abilities. Now active, the enzyme cleaves itself and then other proteins ...

[13] HIV genotypic assays detect specific mutations or nucleotide substitutions in the gag-pol region of the HIV-1 genome. This region encodes for the reverse transcriptase and protease enzymes ...

Brain disorders like Parkinson's or Alzheimer's Disease start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or ...

Brain disorders like Parkinson's (PD) or Alzheimer's Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages ...

we used SEC isolation methods that we previously developed to isolate most EVs from plasma together with an optimized 'proteinase protection assay' where we use an enzyme to gently but efficiently ...

This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...

Thus, qPISA offers a versatile approach for profiling protease and especially exopeptidase specificity, facilitating insight into enzyme mechanisms and biotechnological ... we examined the extent of ...

To achieve this, we combined a high-yield size-exclusion chromatography protocol with an optimized protease protection assay and Single Molecule Array (Simoa) digital enzyme-linked immunoassays ...

FMI researchers have developed a new tool that maps how proteases—enzymes that process proteins—cut their targets. This ...