Kriwacki's investigations into p14 ARF function began when the protein, upon increased expression,was found to localize to the nucleolus. Through interaction with nucleophosmin, a protein abundant ...

This leads to ribosome production arrest and a potentially alternative way p14 ARF elicits its tumor suppressor function. “Upon overexpression, p14 ARF can go to the nucleolus and block ...

Kriwacki's investigations into p14 ARF function began when the protein, upon increased expression, was found to localize to the nucleolus. Through interaction with nucleophosmin, a protein ...

November 11, 2024) There are processes in the human body that can suppress the growth and proliferation of cancer cells.

So, nucleophosmin gets stuck in the nucleolus, and consequently ... since condensates usually rely on fluid dynamics to achieve their function, with solidification often associated with a disease ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, ...

The nucleolus is not just a structure- it's a longevity regulator! Studies suggest that its size could predict how long a cell has left to live. #antiaging #longevity #medindia’ As people age ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators.

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to ...