Exosomes released by mesenchymal stem cells may help reduce vascular remodeling and ease PH symptoms, a rat study showed.

However, the molecular mechanisms by which GDF11 can reduce cardiac fibrosis are incompletely described. Hypothesis: GDF11 is known to activate both NF-kB as well as SMAD2/3 signaling which are ...

The consequences of these chemical changes may include MPT pore opening, activation of redox-sensitive kinases and transcription factors, such as AP-1, NF-kB, and p53. This may lead to alterations ...

Researchers investigate the effects of microplastic exposure on the normal aging and function of adipose tissue.

Exscientia plc (Nasdaq: EXAI) today announced three abstracts to be presented at the 36th EORTC-NCI-AACR (ENA) Symposium 2024 ...

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and ...

Molecules that produce hydrogen sulfide and specifically target mitochondria significantly reduced weight gain in mice.

A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy.

Universitatsklinikum Bonn. (2024, September 26). Central mechanism of inflammation decoded. ScienceDaily. Retrieved October 17, 2024 from www.sciencedaily.com / releases / 2024 / 09 / 240926131931.htm ...

Designing strategies to treat toxin exposure is best accomplished by a detailed understanding of the mechanisms involved in individual circumstances. It is crucial to have knowledge of the role of ...