New drugs that target "zombie" tuberculosis (TB) cells are now a step closer, thanks to a new study led by the University of ...

A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the ...

When Mycobacterium tuberculosis enters a human cell, the presence of its DNA and a molecule that it makes called c-di-AMP alert the cell to the bacteria's presence. The human cell responds by creating ...

Tuberculosis virulence factor identified, ... Sintim and colleagues tested their hypothesis by creating a mutant of Mycobacterium tuberculosis that lacked the CdnP protein and tested it in a mouse ...

The human pathogen Mycobacterium tuberculosis uses a protein secretion system called ESX-1 to export virulence factors that neutralize host defences. ESX-1 is known to be critical for virulence in ...

Researchers were studying the bacteria in question, Mycobacterium tuberculosis, ... The feedback allows the bacteria to maintain a finely-tuned level of virulence.

Restoration of genes lost during the original attenuation of the commonly used BCG tuberculosis vaccine enhances the ability of a recombinant strain to protect against Mycobacterium tuberculosis.

Tuberculosis is a chronic bacterial disease caused by the infective agent Mycobacterium tuberculosis.In 2014, 9.6 million cases of tuberculosis and 1.5 million deaths were recorded throughout the ...

The Rv0455c protein of Mycobacterium tuberculosis, previously annotated as a protein of unknown function, has been shown to function in siderophore secretion. Siderophores acquire iron from the ...

Tuberculosis is an infectious disease caused by a bacterium called Mycobacterium tuberculosis (Mtb), ... Stewart T. Cole. Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence ...

The authors observed that M. marinum mutants with a disabling mutation at the ESX1 locus, a chromosomal region critical to the virulence of M. tuberculosis, 2 are able to infect phagocytes but do ...

Cite this article. Tiwari, P., Arora, G., Singh, M. et al. Correction: Corrigendum: MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence ...