Researchers have developed an RNA-seq method for investigating drug-resistant infections, and we got the inside scoop!

Scientists discovered genes in the tuberculosis bacterium that becomes essential for the pathogen's survival when it's exposed to air through coughing. These genes could be targets for new therapies ...

Seventeen Oxford University researchers have been awarded £5 million to develop new therapies for drug-resistant tuberculosis ...

For 2007, the WHO estimated 511,000 cases of multidrug-resistant (MDR ... rapid and reliable methods for drug-susceptibility testing (DST) of Mycobacterium tuberculosis. For years, proportion ...

Public health officials hoped that antibiotics would eradicate tuberculosis. However, true to its evolutionary tenacity, the disease has mutated into strains of drug-resistant TB, defined as ...

TMC207 is a first-in-class anti-TB diarylquinoline (also named R207910 or the 'J' compound) with activity against drug-sensitive and drug-resistant TB. TMC207 inhibits the proton pump of ...

Since 1990, tuberculosis rates in the U.S. had been dropping, the result of aggressive control programs and anti-tuberculous drugs. Beginning in 2020, rates have risen every year. It is still not ...

Tuberculosis (TB ... models on over 52,000 MTBC isolates to associate binary resistance phenotypes for 15 antitubercular drugs with variants extracted from candidate resistance genes, and generate ...

Scientists at Roche and Harvard University have discovered an entirely new class of antibiotic that can kill a highly drug-resistant ‘superbug’ with a mortality rate that can be upwards of 50% ...

The panel’s recommendation represents a promising step toward eliminating a burden that has hindered access to this crucial medication for patients with treatment-resistant mental illness.

New antibiotics must be used sparingly to delay resistance, reducing their profitability compared with drugs for chronic conditions. Estimates suggest that developing a new antibiotic can cost up ...