For the first time, researchers have discovered that the accumulation of aged and failing cells, called senescent cells, in ...

Multiplex immunofluorescence of a patient’s colorectal cancer liver metastasis showing the diversity of cell states from normal intestinal states (dark blue) to highly plastic injury repair ...

The aging and failure of cells that occurs when the liver is damaged can spread to other organs, suggests a new study in mice ...

The aging and failure of cells that occurs when the liver is damaged can spread to other organs, suggests a new study in mice ...

Metastasis remains the primary challenge to reducing cancer deaths worldwide, says Memorial Sloan Kettering Cancer Center (MSK) gastrointestinal oncologist Karuna Ganesh, MD, Ph.D.. That's when a ...

Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease. Current efforts to ...

Histology, Sirius red staining, immunohistochemistry, and immunofluorescence staining. Liver tissue sections 5 ... expression in bile duct epithelial cells, frozen sections were air-dried, fixed ...

The researchers collected a trio of samples from each of 31 patients — from their primary tumor, nearby healthy tissue, and metastatic tissue (usually from the liver). The researchers then used single ...