New research offers a potential explanation for the formation of early Earth protocells. Few questions have captivated ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ...

Cells in the body have receptors that detect ... They found that some lipid structures, based on their nitrogen chemistry, ...

Messenger ribonucleic acid (mRNA)-based therapeutics and the potential of mRNA as a treatment for various conditions has been ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ...

This work appears in Nature Chemistry. Life on Earth requires lipid membranes – the structure of a cell that houses its interior mechanics and acts as a scaffold for many biological reactions. Lipids ...

Lipid nanoparticles made from lipids optimized via directed chemical evolution show high performance as mRNA delivery vehicles ...

Researchers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ...

Variability among lipids affects cellular metabolism, signaling pathways, energy storage, and cell membrane structures. Therefore, it’s important for biomanufacturers to have an accurate ...

Engineers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids -- key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...