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Immunogenic peptides were derived from framework regions of the variable regions of the immunoglobulin that were shared among patients.
Learn about June 2025’s top biotech deals, featuring major collaborations in small molecules, protein therapeutics, and ...
At a lymphoma conference, experts sparred about treatment options, while an outside expert highlighted the value of each approach.
Results from the Phase III KEYNOTE-689 trial show that adding perioperative Keytruda (pembrolizumab) to standard-of-care radiotherapy improves event-free survival in patients with resectable, locally ...
A pregnant, primiparous 32-year-old woman at 28 weeks’ gestation presented for a routine prenatal visit. Blood work showed thrombocytopenia with platelet count of 60 (reference range 130–380) × 109/L.
Some two dozen biotech developers of PROTACs, molecular glues and other types of protein-degrading drugs have sprung up over ...
Moreover, antibodies may also provide an important function by neutralizing antigens and promoting their clearance. In addition, B cells mediate functions independent of antibody production, such as ...
Immunoglobulins operate by recognising specific antigens via their variable domains while utilising their constant (Fc) domains to engage immune receptors and modulate effector functions.
A pioneering new study published in Nature Microbiology, led by J. Oriol Sunyer, professor of immunology and pathobiology at ...
Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...
The global Custom Antibody Market is valued at USD 553.05 Million in 2024 and is projected to reach a value of USD 1237.1 ...
The authors investigated the potential role of IgG N-glycosylation in Haemorrhagic Fever with Renal Syndrome (HFRS), which may offer significant insights for understanding molecular mechanisms and for ...