New study findings may provide the key to overcoming treatment resistance in small cell lung cancer, according to researchers at The University of Texas MD Anderson Cancer Center. In a study led ...

Characterization of heterogeneity in three lung cancer patients with multiple nodules by whole exome sequencing. Dongcheng Liu, Shixuan Li, Jiaqing Wang, Xuefeng Sun, Guofeng Li, Bin Peng, Peikun Ding ...

The findings reveal a heterogeneous lung cancer ecosystem, with extensive interactions between cancer cells and the surrounding microenvironment that regulate early cancer development.

Mark A. Socinski, MD, discussed how the understanding of lung cancer has evolved over time, as well as how its heterogeneity impacts treatment strategies. Mark A. Socinski, MD, executive director ...

The findings reveal a heterogeneous lung cancer ecosystem, with extensive interactions between cancer cells and the surrounding microenvironment that regulate early cancer development.

In Barrett's esophagus, the higher the diversity in a single biopsy the worse the prognosis. 17 Heterogeneity in HER2 amplification is associated with a higher cancer-specific death rate. 18 Similar ...

Small cell lung cancer (SCLC) accounts for 14% of all lung cancers and is often rapidly resistant to chemotherapy, resulting in poor clinical outcomes. Treatment has changed little for decades ...

Through studies in mouse models, the team demonstrated that inactivation of MMR is not enough to improve patient responsiveness to ICB. They found that mouse models of MMRd lung and colon cancers ...

The primary outcome was an increased risk for lung cancer associated with GERD. The analysis included 10 studies with at least 2,302,272 participants, with 90% of the studies using international ...