By contrast, in the hepatocyte lineage (Wesley et al., 2022), every NAD de novo Synthesis Pathway gene was expressed by 5 PCW (hepatoblast (HB) stages 1 and 2; Figure 6H) and remained constant ...

A unique, specific marker for LSCs in the adult liver has not yet been assigned, and because these cells are not under constant renewal, unlike epithelial cells of the intestine or the skin, they ...

In this valuable study, Seidel et al. identify and characterize a novel subset of hepatocellular carcinoma patient-derived xenograft models defined by active Jagged 1-Notch2 signaling and a ...

2Dr. Li Dak-Sum Research Centre, the University of Hong Kong, Hong Kong 3Department of Surgery, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 4Department of Surgery, ...