Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found.

Patients with ovarian clear cell carcinoma (OCCC) whose tumors have specific mutations in the PPP2R1A gene were found to have improved survival following immunotherapy compared to patients without ...

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain ...

NNRTI-resistance Mutations & their Mechanism of Drug Resistance The latest list of drug-resistance mutations for HIV clinical practitioners [36] indicates that NNRTI resistance is associated with ...

Clinical studies on HIV-2-infected patients treated with ART demonstrated both the high prevalence of the Q151M mutation associated with multi-NRTI resistance (9–50% in NRTI-experienced patients ...

Beyond selectivity concerns for thyroid hormone receptor β (THR-β) agonists, intolerance to the His435 mutation remains a challenge. Following our previous study, we performed detailed modifications ...