Glutamate derived γ-aminobutyric acid (GABA) is synthetized in the cytosol prior to delivery to the mitochondria where it is catabolized via the TCA cycle. GABA accumulates under various environmental ...

Specifically, levels of glutamate, aspartate and asparagine are all significantly decreased in the IND-cKO retina prior to PR degeneration, which demonstrates that similar to the GLS cKO mouse (i.e.

When glutamate is too high and GABA levels are too low, as is the case with fibromyalgia and ME/CFS, symptoms like hyperalgesia (heightened sensitivity to pain), anxiety, restlessness, brain fog, ...

The presence of glutamate reprogrammes the metabolism of macrophages, and these consequently begin to secrete a growth factor that leads to an increase in hepatocyte production. In other words, a ...

In other words, a rapid chain of events allows glutamate to trigger liver regeneration in just minutes, through changes in the macrophage metabolism. It is, says Djouder, "a new, complex and ...

The presence of glutamate reprogrammes the metabolism of macrophages, and these consequently begin to secrete a growth factor that leads to an increase in hepatocyte production.

Glutamate is the most abundant excitatory neurotransmitter in the brain and is necessary for proper brain functioning. Excitatory neurotransmitters are chemical messengers that excite, or stimulate, a ...

Beyond its direct impact on treating red blood cell disorders, the findings suggest that metabolic features such as glutamine–to–glutamate ratios can be used as biomarkers for many other diseases.

Glutamate decarboxylase (GAD) is the key enzyme for the production of gamma-aminobutyric acid (GABA), a multifunctional agent which biosynthesis has attracted intense interest. Though immobilized GAD ...

Monosodium L-glutamate in soup reduces subsequent energy intake from high-fat savoury food in overweight and obese women. https://pubmed.ncbi.nlm.nih.gov/26455957/ Trusted Source ...