Two kinase inhibitors have been recommended by the European Medicines Agency for the treatment of non-small cell lung cancer.

The detection of MRD mutations in postoperative plasma samples was also found to be associated with patient prognosis, with patients having fusion ... small cell lung cancer with gene fusions ...

Oncogene 2008; 27:2084-90. Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008; 14:4275-83. Stergianou K, Fox ...

Targeted therapy revolutionized cancer treatment, with gene fusions leading the way when the FDA approved imatinib in 2001 to ...

This second finding led the researchers to argue that there is genetic basis for both lung cancer and nicotine dependence. In other words, based on the researchers' interpretation of the evidence ...

Gene fusions are vital biomarkers for tumor diagnosis and drug development, with precise detection becoming increasingly ...

Bristol Myers Squibb on Friday said the European Medicines Agency's Committee for Medicinal Products for Human Use recommended expanded approval of its Augtyro cancer drug in a pair of indications.

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, ...

The team analyzed genetic data from the UK 100,000 Genomes Project to identify DNA changes that cause cells to become ...

One patient to benefit from the test was Kat Robinson, 33, from Dorset, who was diagnosed with stage 4 lung cancer in September 2023. The test, done at Poole Hospital, identified two key genes driving ...

Lung cancer is one of the most critical global health threats, as the second most common cancer and leading cause of cancer deaths globally. While smoking is the primary risk factor, an increasing ...

In operable non-small cell lung cancer (NSCLC), molecular residual disease (MRD) detection via circulating tumor DNA (ctDNA) has emerged as a ...