Oocytes are long-lived cells that require specialized adaptations to maintain their fitness. This study shows that human ...

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their ...

Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single ...

A new study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix.

Exocytosis, the fusion of secretory vesicles with the plasma membrane to allow release of the contents of the vesicles into the extracellular environment, and endocytosis, the internalization of ...

Researchers at Washington University School of Medicine in St. Louis have revealed the structure of a key protein involved in ...

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...