Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science Translational Medicine , 2024; 16 (731) DOI: 10.1126/scitranslmed.add6883 Cite This Page : ...

Children with Down syndrome and congenital heart defects may have gastrointestinal, respiratory or neurologic issues, along with endocrine disorders such as diabetes or thyroid dysfunction.

The largest genetic study of congenital heart defects in individuals with Down syndrome found a connection to rare, large genetic deletions affecting cilia, scientists report. The high risk for ...

A donor heart saved Charlotte Woodward's life 13 years ago. Now Woodward, 35, is fighting for others with Down syndrome or other disabilities to have the same chance. Research has shown that people ...

According to the National Down Syndrome Society, these heart defects are due to a fault in the lungs of those living with this syndrome. In other words, the lungs of children suffering from DS do ...

Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21.

Down syndrome increases the risk of Alzheimer’s disease. People with Down syndrome may experience health problems as they age that are similar to those experienced by older people in the general ...

6-Month-Old Baby Born with 3 Heart Defects and Down Syndrome Defies the Odds. Bonnie Witaschek says her daughter, Kitty, was born with three heart defects, a stomach defect and has Down syndrome. By.

“When she gets that yellow belt, she’s going to be walking on cloud nine,” J.J. Moody said about her daughter’s goal.

Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21. Reducing ...

Leveraging genetic mapping, scientists pinpointed a gene on human chromosome 21 named Dyrk1a. In the mouse model of Down syndrome, having three copies of this gene leads to heart defects.While ...