Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands.

As climate conditions become increasingly unpredictable, understanding how plants respond to cold is crucial for securing ...

Scientists have identified the 1N4R tau isoform as a key driver of Alzheimer’s disease, paving the way for potential new ...

The amyloid-β precursor protein (APP) helps to form links between the brain’s neurons. It has been highly studied because its ...

Researchers found that TEX38 and ZDHHC19 co-localize on the plasma membrane of spermatids and mediate S-palmitoylation of ARRDC5, a crucial protein for spermatogenesis. Disrupting either TEX38 or ...

As well as degrading proteins, the proteosome surprisingly also functions in human defence against bacterial infection. By ...

Researchers discovered AP2A1, a protein controlling cellular aging. Lower AP2A1 reversed aging effects, while higher levels ...

Proteins play a key role in the life sciences - from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals.

Department of Biotechnology, Bhupat & Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

The class II clustered regularly interspaced short palindromic repeats (CRISPR)–Cas systems, characterized by a single effector protein, can be further subdivided into types II, V, and VI. The ...

This review provides the latest advancements in research on the regulatory roles of non-histone protein lactylation, highlighting its crucial scientific importance for future studies. Figure 1. The ...