This work is published in Nature in the article, “Clonal tracing with somatic epimutations reveals dynamics of blood ageing.” In youth, humans have between 50,000 to 200,000 active blood stem ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele ...

As with standard speed Twist Clonal Genes, Twist Express Genes are NGS sequence-verified and one hundred percent accurate. Twist Express Genes can be cloned into catalog vectors or custom vectors ...

Siphonophores are unusual animals made up of individual organisms called "zooids," which each have a distinct function — despite being genetically identical. When you purchase through links on ...

Image credit: Mangkelin/Getty Images. Their two recent studies have uncovered new information about clonal hematopoiesis and its treatment with the anti-inflammatory drug colchicine. Researchers ...

Study: Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis. Image Credit: BioFoto / Shutterstock ...

Amgen subsidiary deCODE Genetics has identified new risk factors and genes associated with clonal hematopoiesis, a precursor state to blood cancer. In the results of a study published Nov. 6 in ...

Clonal hematopoiesis is a condition that arises when a single clonal lineage of hematopoietic stem cells (HSC) expands and becomes the source of a substantial proportion of mature blood cells. The ...

Fig 1. Schematic overview of clonal expansion of HSCs in CH and the associated clinical consequences of circulating CH-mutant HSC clones. After somatic mutations in a driver gene, the selective ...

Please provide your email address to receive an email when new articles are posted on . Clonal hematopoiesis of indeterminate potential, which has been shown to substantially increase risk for ...

The mutations that cause some of our blood stem cells to multiply faster than others form their own distinct populations or “clones,” known as clonal hematopoiesis. People with clonal ...

delayed generation of clonal anergy. These five mechanisms are insufficient to induce tolerance when the donor-recipient combinations are disparate in MHC antigens plus minor H antigens as is seen in ...