Androgen deprivation is the mainstay of advanced prostate cancer treatment. Despite initial ... of skeletal-related events (SREs) in bone metastatic CRPC (mCRPC). Denosumab compared with ...

This drug approval followed the publication of the EMBARK trial, a randomized phase III trial of biochemically recurrent patients who had high-risk disease, defined by a PSA doubling time (PSADT) ≤9 ...

A Cork University Hospital trial of physical therapy for men battling metastatic cancers of the urinary tract and reproductive systems – and named with a nod to a hurling legend – is already ...

As further agents are developed for metastatic castrate-resistant prostate cancer, there will be a growing need for clarity on treatment sequencing, and for cancer care commissioners to understand ...

The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) has announced funding for a new project aimed at improving management of side effects caused by poly ...

The most common sites of metastasis were bone (554 patients), brain (71 patients), liver (237 patients) and lung (115 ...

As many as 20% of soft tissue sarcomas and up to 40% of bone sarcomas develop lung ... imaging studies may provide enough evidence of metastases, although a biopsy may be needed to confirm the ...

Cancer is one of the most formidable health challenges of our time, affecting nearly half of us during our lives. While treatments have significantly improved in recent decades, the biggest challenge ...

Metastatic breast cancer diagnoses are rising in U.S. women, especially in younger age groups and racial minorities, as ...

but their translation into clinical practice is hindered by variations in metastasis, treatment responses, and resistance. New therapeutic strategies, while efficient, face issues due to cancer ...

Two million bone transplants are performed worldwide yearly, including half a million in the United States alone. Yet, a ...

Objective The optimal approach to the treatment of colorectal carcinoma and synchronous liver metastases remains controversial. The objective of this review was to analyze the outcomes of adopting the ...