The germinal centre (GC) of lymphoid organs is the main structure where antigen-activated B cells diversify their immunoglobulin genes by somatic hypermutation (SHM) to generate high-affinity ...

But Ruffin was one of the first to observe this exhaustion in memory B cells in and near tumors, outside of the tertiary lymphoid structure. “Historically, B cells have largely been ignored in the ...

But Ruffin was one of the first to observe this exhaustion in memory B cells in and near tumors, outside of the tertiary lymphoid structure. "Historically, B cells have largely been ignored in the ...

But Ruffin was one of the first to observe this exhaustion in memory B cells in and near tumors, outside of the tertiary lymphoid structure. "Historically, B cells have largely been ignored in the ...