ALK’s peanut tablet shown to be safe and tolerable across multiple doses.Development now advances to phase II for dose finding and efficacy.

The drug candidate acts by targeting anaplastic lymphoma kinase (ALK). Nuvalent is a clinical-stage biopharmaceutical ... as it considers the probability that the drug never makes it through the ...

Dr. Alison Moskowitz presented results of a Phase 1 study of combination duvelisib plus ruxolitinib in relapsed/refractory (R ...

The evidence for the authors' claims is convincing, combining state-of-the-art conditional gene deletion in the mouse lens with histological and molecular approaches. This work should be of great ...

In preclinical studies, investigational ARO-ALK7 silenced Activin receptor-like kinase 7 (ALK7) expression in adipose tissue, which led to reduced body ...

Roads and pathways in the region were flooded, trapping residents in their homes. “The floodwaters are rising by the hour.

Students who will be freshman next fall will be the first class to transition to the College and Career Pathways model. “It’s a program that’s designed to help our students become more ...

It also activates the Wnt/β-catenin pathway, promoting β-catenin nuclear localization and upregulating target genes such as Lef1 and ALP. Our findings suggest that Gpr54 deletion may accelerate the ...

During your time with Pathways to Medicine, you will participate in events and activities throughout Year 12 and 13. Every aspect of the programme is designed to help you make a strong and informed ...

Some students have said they weren’t made aware of the alternative pathways available. As thousands of high school students across Australia anxiously await ATAR results, many first-year ...