Alagille Syndrome (ALGS) is a genetic disorder ... and exploring treatment options, particularly liver transplantation. Recent studies have provided valuable insights into the management and ...

The liver of a child with Alagille syndrome ... One study found that the mean age of children with Alagille syndrome at the time of transplantation was seven years and ten months.

HYDERABAD : A liver transplant procedure was successfully performed on a 12-year old boy who was suffering from a rare genetic disease, Alagille syndrome, at city-based Care Hospitals, giving him ...

Its genetic polymorphism is known to strongly influence tacrolimus disposition and daily dose requirements in renal transplant recipients. During liver transplantation, the CYP3A5 expressor or ...

Ipsen has said that it plans to file a new marketing application for its treatment for itch in Alagille syndrome (ALGS ... for patients to seek a liver transplant. “We stand by our commitment ...

in patients with the rare liver disease Alagille syndrome (ALGS). Kayfanda (odevixibat) is labelled in the EU to treat cholestatic pruritus – itching caused by impaired bile formation or flow ...

Aim: Little information is available regarding the influence of CYP3A5 genetic polymorphisms on tacrolimus dose requirement in pediatric liver transplantation. Patients & methods: We performed a ...