The main autoantigens associated with APS are phospholipids. Antiphospholipid antibody (aPL) describes antibodies that attack certain proteins that bind the phospholipid cell walls of blood cells ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

In the present work, we explore phospholipid bilayer nanodiscs as membrane mimics and employ electron microscopy and solution NMR spectroscopy to characterize the structure and function of the human ...

Phospholipid-binding domains vary widely in their degree of ligand specificity. Some are highly target specific, whereas others will bind to any acidic phospholipid. Target-specific domains ...

Phospholipid fatty acid (PLFA) method has been popular and powerful for characterizing soil microbial communities over decades. However, little is known about efficiencies of acidic vs. alkaline ...

The present molecular dynamics simulations together with time-dependent fluorescence shift experiments suggest that the mode and strength of interaction of calcium ion with a phospholipid bilayer ...