SportsLine's NFL model locked in its Thursday Night Football NFL anytime touchdown picks for Los Angeles Rams vs. San ...

The San Francisco 49ers announced that Dr. Harry Edwards has been named as the team’s 2024 Inspire Change Changemaker.

SportsLine's team of Vegas experts, NFL model, and AI PickBot just revealed the top 49ers vs. Rams NFL betting preview ...

The Los Angeles Rams hope to come away with the same result tonight as they had in Week 3 when they hosted the San Francisco ...

The 49ers have a dilemma. The core of their roster is too old and too expensive. They need to cut some of these overpaid veterans and reload for the future. Which brings us to George Kittle.

Sunday night as snow fell throughout Buffalo’s Week 13 home game against San Francisco. For the Bills, the conditions were ...

Playing in below-freezing temperatures and in the snow, the Buffalo Bills (10-2) defeated the San Francisco 49ers (5-7), 35-10, at Highmark Stadium. The 49ers took an early 3-0 lead in the first ...

The 49ers have poured millions of dollars into their home city’s council races on a biannual basis over the past three election cycles and beyond. Bay Area News Group reported the team’s ...

Christian McCaffrey is dealing with another long-term injury again. The San Francisco 49ers running back went down with a knee injury during the second quarter of the team's "Sunday Night Football ...

San Francisco 49ers general manager John Lynch has dismissed any speculation that Kyle Shanahan won't be the team's head coach in 2025. Appearing on KNBR's Marcus & Murphy show on Friday ...

The 49ers won't have the left side of their offensive line this Sunday when they face the Bills. Left guard Aaron Banks will miss the 49ers' Week 13 game with a concussion he suffered last week in ...