Instead of being used for something, the codon was freed up to be redefined. The researchers did similar experiments with the codons for the amino acid serine.

Article #20-14567: "Evolution of the genetic code; Evidence from serine codon use disparity in Escherichia coli," by Masayori Inouye, Risa Takino, Yojiro Ishida and Keiko Inouye.

The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...

He and his team systematically replaced every occurrence of the serine codon TCG with AGC, every TCA (also serine) with AGT, and every TAG (stop) with TAA, for a total of 18,214 replacements.

In the CDR3 of VL there are two hot spots of the A/G-G-C/T-A/T type and one AGT serine codon. We began our experiments by concentrating on the tetranucleotide hot spots in VL CDR3.

While humans (and just about everything else) translate the codon CTG as the amino acid leucine, some of the species of yeast instead translate this as the amino acid serine whilst others ...

Therefore the code is not universal, although it can be called widespread as, for example, the codon TCT codes for serine in any organism. The editor writes • Joe Mortimer is correct.

In humans and most other living things, the codon CTG translates to the amino acid leucine. But in this yeast family, some members use the sequence to create serine, while others make alanine out ...

Every time this codon is translated the cell tosses a chemical coin: heads for leucine, tails it's serine.