‘synonymous sites', includes those that encode ‘degenerate' positions in the codon table, where a change does not lead to an amino acid substitution. For example, TCT and TCC both encode serine.

The V600E missense mutation in the cytosolic serine–threonine kinase BRAF leads to its constitutive activation (independently of upstream regulation by RAS at the plasma membrane, as shown in ...

In the table, M represents methionine, A represents alanine, K represents lysine, S represents serine, and T represents ... The tRNA that corresponds to the second codon can then bind to the ...

1 Alternative splicing will sometimes introduce a premature stop codon into an mRNA, which NMD will recognize as an mRNA that needs to be degraded. “It's a very common mechanism of downregulation,” ...

At high density and in tumours TNBC cells produce MUFAs via SCD and secrete lipid-bound MUFAs that protects them from ...