Tisch, 43, the Harvard-educated scion of a wealthy New York family, has worked for the city for 16 years, holding leadership roles in several agencies. As sanitation commissioner, she became TikTok famous when she declared in 2022, “The rats don’t run the city, we do.”

Tisch will make history as the second female to serve in this role, following Commissioner Keechant Sewell, who was appointed by Adams as the first female commissioner in the department's 179-year history.