Claudin-1, a tight junction protein expressed in human liver, has been identified as an essential entry co-factor for hepatitis C virus. Like the CD81 co-receptor, claudin-1 spans the cell ...

Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP. Nature Communications , 2024; 15 (1) DOI: 10.1038/s41467-024-46706-w Cite This Page : ...

However, a recent study published on the preprint server bioRxiv in November 2020 uncovers the major role played by the N-terminal domain of the SARS-CoV-2 virus in host infection. This could be ...

Hence, ACE2 acts as a cellular doorway—a receptor—for the virus that causes COVID-19. ... The virus reaches the lungs after entry in the nose or mouth. ANG II drives lung injury.

DENV Attachment: Multiple Cell Receptors? The events involved in virus entry comprise virion binding to the cell surface followed by penetration into the cytoplasm. The success of both sequential ...

Porcine reproductive and respiratory syndrome virus (PRRSV) continues to devastate the global swine industry, yet the ...

However, at present this coronavirus, called NeoCoV and a similar virus, PDF-2180, only weakly bind to human ACE2 cell receptors as an entry point into cells.

To study non-enveloped virus cell entry, a versatile in vitro model system was developed in which liposomes containing nickel-chelating lipids were decorated with His-tagged poliovirus receptors ...

There is a current lack of effective therapeutics with which to fight SARS-CoV-2. Could creating a "trick" version of the ACE2 receptor, the virus' entry point into cells, be the answer? We speak with ...

In bats, two close virus relatives of the coronavirus MERS-CoV, the cause of Middle-East Respiratory Syndrome, use the ACE2 receptor as an entry point into bat cells. These receptors have some ...

New research shows that the closest bat virus relatives of the human Middle-East Respiratory Syndrome (MERS) coronavirus efficiently bind to bat ACE2 receptors as an entry point into these cells.