Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis (Mtb), which causes tuberculosis featuring lung ...

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of ...

TB is caused by a type of bacteria called Mycobacterium tuberculosis ... a protein that’s produced by a type of immune cell called T cells. You can also get a skin test to check for the bacteria.

Researchers have engineered two mycobacterial strains with built-in kill switches that trigger self-destruction after immune ...

Every year, 10 million people contract tuberculosis (TB ... which surrounds a layer of immune cells and a core of dead tissue (necrotic core) where the bacteria can hide and survive.

A new vaccine that boosts immunity against tuberculosis (TB) has been shown to be effective in pioneering pre-clinical trials.

Tuberculosis remains one of the most lethal infectious diseases caused by a single pathogen. According to the latest global ...

Tuberculosis, the world’s oldest and deadliest pandemic, has been plaguing us for well over 4,000 years, with a relative of TB bacteria detected since the dinosaur age, and an ancestor having ...

Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models. Nature Microbiology , 2025; 10 (2): 482 DOI: 10.1038/s41564-024-01913-5 ...

Every year, 10 million people contract tuberculosis (TB ... which surrounds a layer of immune cells and a core of dead tissue (necrotic core) where the bacteria can hide and survive.

Römpp, A., Treu, A., Kokesch-Himmelreich, J. et al. The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis. Nat Commun 16, ...