Dinsmore and colleagues investigated the efficacy and safety of topical eutectic lidocaine–prilocaine mixture for premature ejaculation (TEMPE), applied to the glans penis via a metered-dose ...

The pharmacokinetics, safety, and tolerability of four topical lidocaine patches 5% continuously applied for 72 hours and changed every 12 or 24 hours were examined. In this randomized ...

However, such responses appear to have increased because of lidocaine's more frequent use in topical therapies. We report on 16 patients who had positive patch-test reactions to lidocaine.

Esophagogastroduodenoscopy (EGD) is a common diagnostic and therapeutic technique with a low complication risk, but which causes considerable patient anxiety. Sedation during endoscopy by ...