Quarterback Brock Purdy is one of the eight 49ers' captains. On Saturday, he shared his perspective in front of the entire ...

Founded in 1946, the San Francisco 49ers have ... as one of the most consistent running backs of his time. NFL Comeback Player of the Year (2001) Second-team All-Pro (1998) 2-time Pro Bowl ...

The San Francisco 49ers running back went down with a knee injury during the second quarter of the team's "Sunday Night Football Game" loss to the Buffalo Bills and never returned. Head coach Kyle ...

There's even a chance Guerendo, who pulled his hamstring on the first day of training camp and missed the first two preseason ...

Christian McCaffrey and Jordan Mason both are on Injured Reserve, and now Isaac Guerendo has a foot/ankle sprain that he ...

The San Francisco 49ers haven't been an underdog for a game since 2022, but that incredible run appears to be coming ... The 49ers have been the favored team in 36 straight games.

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers ...

Kyle Shanahan and the San Francisco 49ers got themselves back on track in Week 14 with a 38-13 victory over the Chicago Bears ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...