Pulmonary surfactant is a lipoprotein complex that consists of a variety of lipids -- primarily phospholipids -- and several proteins. The function of surfactant is to prevent lung collapse ...

Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of ...

KL4 Surfactant is under clinical development by Windtree Therapeutics and currently in Phase II for Coronavirus Disease 2019 (COVID-19) Associated Acute Respiratory Distress Syndrome.

Zelpultide alfa is under clinical development by Airway Therapeutics and currently in Phase I for Coronavirus Disease 2019 (COVID-19).

Endothelial inflammation, as measured by E-selectin, was significantly associated with hypoxemia measures, even after adjusting for BMI.

Pediatr Crit Care Med. 2013;14(6):631-643. Future studies of the effect of exogenous surfactant in children and adults with ARDS should use the same surfactant and include a study design that can ...