The pharmacokinetics of promethazine administered in oral syrup and rectal suppositories were highly variable, but, in general, the suppositories produced a lower C max and later t max than the syrup.
Promethazine HCl 6.25mg, dextromethorphan HBr 15mg; per 5mL; liq; contains alcohol 7%. Dextromethorphan is an antitussive agent and, unlike the isomeric levorphanol, it has no analgesic or ...
Codeine phosphate 10mg, promethazine HCl 6.25mg; per 5mL; syrup; contains alcohol 7%. Risk of life-threatening respiratory depression and death related to ultra-rapid metabolizers of codeine (esp.
After enrollment and completion of study period 1 (treatment D, 50 mg [10 mL] of promethazine oral syrup), one subject was withdrawn from the study because of violation of study protocol.