"By activating the STING pathway, the drug promotes ... Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer, Cell Reports Medicine (2024).

The enveloped self-amplifying mRNA CARG-2020 modulates IL-12, IL-17 and PD-L1 pathways to prevent tumor recurrence. VLV vectors were designed to deliver single chain interleukin (IL)-12, short-hairpin ...

Researchers from Tianjin University have published data regarding development and preclinical characterization of a new anti-PD-L1/CD40 bispecific antibody (BsAb), BA-4415, designed to activate CD40 ...