Only in arginine-deficient citrulline-based medium, the ornithine cycle appears to be expressed in a more normal way, as the citrulline concentration hardly changes during an incubation with ...

Why? Because clams are jam-packed with ornithine, the amino acid that doubles as a hangover remedy. “L-ornithine’s therapeutic value lies in its involvement in the urea cycle and its ability to ...

Shares of Arcturus Therapeutics Holdings Inc. (NASDAQ:ARCT) edged up 2% after the company shared encouraging interim results from two Phase 2 trials evaluating its investigational mRNA therapy, ...

Ornithine transcarbamylase deficiency is a urea cycle disorder caused by a genetic mutation in the OTC gene resulting in excess levels of ammonia in the blood.

The group found that the switching on of the urea cycle causes the production of ornithine, another metabolite that accumulates in the cell and needs to be cleaned up.

Cycle 1: The ornithine cycle A year after leaving Warburg's laboratory, Krebs obtained a clinical post at the hospital of his old medical school in Freiburg.

L-ornithine-L-aspartate (LOLA) is not frequently used as there are still some reservations about its benefits. The present study aimed to assess the effectiveness and safety of LOLA in the ...

Because putrescine’s biochemical precursors, arginine and ornithine, are part of the urea cycle, Ju and colleagues examined how this cycle changed in response to Aβ. In astrocytes exposed to 1 μM ...

Researchers have found that that a mutant strain of sake yeast produces high levels of the amino acid ornithine. Ornithine has been found to reduce fatigue and improve sleep quality, and the non ...

Ornithine Decarboxylase mRNA expression as a prognostic biomarker in patients with curatively resected NSCLC is examined.

About Ornithine Transcarbamylase Deficiency Ornithine transcarbamylase (OTC) deficiency is the most common urea cycle disorder.

Arcturus Therapeutics Holdings Inc. (the "Company", "Arcturus", Nasdaq: ARCT), a commercial messenger RNA medicines company ...