Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

Increasing data support new nucleolus functions, including signal recognition particle assembly, small RNA modification, telomerase maturation, cell-cycle and aging control, and cell stress sensor.

"The nucleolus performs a specialized function, and NPM1 seems to have evolved to assist in the process by being able to phase separate with these two important and very different types of ...

Although known since the 1830s as a round, dark spot in a cell's nucleus, only recently has the nucleolus gotten its full due. Scientists, including research conducted by the lab of Clifford ...

Study explains how part of the nucleolus evolved A single protein can self-assemble to build the scaffold for a biomolecular condensate that makes up a key nucleolar compartment ...

What we've learned about the nucleolus since you left school. Cell Press. Journal Trends in Cell Biology DOI 10.1016/j.tcb.2018.03.007 ...

Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known for its role in protein production, functions as a biological timer that could determine cellular lifespan.

Ultimately, the condensates localized on the nucleolus, compromising its function. Details about this sequence of events appeared in Nature, in an article titled, ...

"In any case, the nucleolus functions as a stress sensor showing us that a cell is in danger." ### Claus Rieker, David Engblom, Grzegorz Kreiner, Andrii Domanskyi, Andreas Schober, ...