Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

These insights into the nucleolus' form and function could ultimately point toward new ways to treat disease. "To get the characteristic layered, 'core-shell' architecture of the nucleolus, all you ...

"The nucleolus performs a specialized function, and NPM1 seems to have evolved to assist in the process by being able to phase separate with these two important and very different types of ...

Study explains how part of the nucleolus evolved A single protein can self-assemble to build the scaffold for a biomolecular condensate that makes up a key nucleolar compartment ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

What we've learned about the nucleolus since you left school. Cell Press. Journal Trends in Cell Biology DOI 10.1016/j.tcb.2018.03.007 ...

Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known for its role in protein production, functions as a biological timer that could determine cellular lifespan.

Ultimately, the condensates localized on the nucleolus, compromising its function. Details about this sequence of events appeared in Nature, in an article titled, ...

A nucleolar protein, nucleostemin, is now implicated in the control of stem and cancer cell proliferation. Nucleostemin may modulate p53 function through shuttling between the nucleolus and the ...

"In any case, the nucleolus functions as a stress sensor showing us that a cell is in danger." ### Claus Rieker, David Engblom, Grzegorz Kreiner, Andrii Domanskyi, Andreas Schober, ...