The mechanism of action of methylphenidate is not completely ... Methylphenidate is thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the ...
However, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms. Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine and dopamine ...