Study by MIT and others identifies genes essential for tuberculosis bacterium’s survival during airborne transmission.

3) Inside macrophages, Mycobacterium tuberculosis dodges intracellular degradation by secreting virulence factors. Two effectors, EsxH and EsxG, inhibit the function of the ESCRT machinery, impairing ...

The COVID-19 pandemic has played a pivotal role in the resurgence of TB. Cases increased globally by 4.6% from 2020 to 2023, reversing decades of steady declines in the disease. In the US alone, TB ...

The WHO warned Wednesday that massive funding cuts, especially from the United States, could harm humanitarian efforts ...

Mycobacterium Tuberculosis secretes molecules called Virulence Factors - the cell’s secret weapon -which block out the immune response to the infection, making it difficult to treat. The team ...

Intriguingly, we showed that a whiB3 mutant of virulent Mycobacterium bovis was completely impaired for growth in guinea pigs. These mutants define a new class of virulence genes in M. tuberculosis ...