Upon ablation of the adipocytes, the macrophages in the remnant fat pads remain behind, but these cells are now no longer inflamed to the same degree due to the absence of the major instigator of ...

Consequently, this impedes the phagocytic process through which macrophages eliminate spent adipocytes. Conversely, ...

Similarly, in obesity, macrophages can engulf fatty acids and dying adipocytes with voluminous lipid content. This may be useful early on, but it gradually compromises macrophage function ...

ZyVersa Therapeutics (ZVSA) highlights newly published data demonstrating cardioprotective effects and improvements in metabolic parameters ...