The BCR- and TCR-mediated immunological synapses are strikingly similar in ... recognition of carbohydrate patterns, bacterial structures, apoptotic cells and debris associated with cell damage ...

The interaction between CD2 and CD58 is critical for forming the immunological synapse, which is pivotal in immune cell activation and adhesion, as well as signaling in both immune and target cells.

Immune cells communicate with each other by bringing critical signaling proteins to their surfaces, forming physical 'synapses' between cells. This movement of resources from the inner part of the ...

A growing cancer is shaped by more than just the tumor cells it contains; the tissue around a tumor also alters its biology.

In the Huse lab, we combine imaging technology with synthetic chemistry and materials science to understand how immune cells communicate. Effective immune responses against infectious agents and ...

They demonstrated that this complex regulates the phosphorylation of many proteins involved in synapse structure and organization. High-resolution imaging of the mutant mice brains revealed ...

They demonstrated that this complex regulates the phosphorylation of many proteins involved in synapse structure and organization. High-resolution imaging of the mutant mice brains revealed ...

The CD2-CD58 axis is associated with the regulation of autoimmune diseases, immune evasion of tumors, antiviral responses, and immune rejection, and targeted therapies for this have been developed.

provide comprehensive insights into beta cell cilia structure, their interaction ... migration, and the immune synapse. Here, Schapfl et al. show that B cell progenitors tolerate centriole ...

The researchers knew that VP3 was necessary for capping messenger-RNA (mRNA), a process essential for the synthesis of viral proteins and for evading the host’s immune response, but while the ...