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Neurona Therapeutics, a clinical-stage biotherapeutics company advancing regenerative cell therapies for disorders of the ...
Dendritic protrusions have a major role in the production of glutamatergic synapses. Much less is known regarding the development of GABAergic connections. This study examined contact formation ...
The authors review the available literature on the preclinical and clinical studies involving GABAergic neurotransmission in mood disorders. γ-Aminobutyric acid (GABA) is an inhibitory ...
Abnormal GABAergic function is associated with a variety of neurological diseases. Hence, understanding neuronal activity is crucial for the discovery of novel treatments and therapeutic drugs. While ...
New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has found that some processes behind the early development of GABAergic neurons, neurons that ...
Discovery of GABAergic synaptic regulations inside the brain for a new epilepsy treatment DGIST joint research team identified the roles of 'Somatostatin,' which mediates the functions of ...
Professor Um said, "We found a key clue that somatostatin, which is a key for regulation of synaptic transmission between nerve cells, directly mediates the development of GABAergic synapses.
The GABAergic findings seem to be specific to tauopathies, however. The authors examined gene expression in postmortem parietal cortex samples from 80 people with late-onset AD, 18 with ...
Mouse midbrain GABAergic neuron subtypes (red), GABAergic neurons associated with the dopaminergic nuclei (purple), Dopaminergic neurons (green). Reference: Laura Lahti. Our studies have revealed ...
SSH analysis identified differential expression of members of the GABAergic gene family in NB. Lower levels of gamma-aminobutyric acid (GABA) receptor–associated protein (GABARAP) gene expression ...
Unlike other inhibitory subtype neurons, it was previously thought that GABAergic PV neurons do not release vasoactive substances, hence their role in blood flow regulation has been controversial.