The human gut is home to helpful microbes, called the microbiota, who produce molecules known as metabolites. These ...

When they tested how different metabolites affected cDC1 cells, they saw an increase in the expression of genes linked to ...

Filopodia (cellular extensions) reach out and contact the clusters directly. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

(A) In a cell, motility is initiated by an actin-dependent protrusion of the cell’s leading edge, which is composed of armlike structures called lamellipodia and filopodia. These protrusive ...

Researchers from Osaka University discover that the GPR31 path in 'gut surveillance' cells detects bacterial metabolites and triggers immune responses, opening new possibilities for drug development, ...

(D) The growth cone contains dendritic actin filament networks and parallel actin filament filopodia. (E) Microtubules consist of 13 protofilaments of tubulin dimers arranged in a hollow tube.

Researchers have discovered that GPR31, found in certain immune cells in the human gut, plays a key role in responding to bacterial metabolites and activating immune responses. Specifically, in the ...