Endocytosis occurs when the cell membrane engulfs particles (dark blue) outside the cell, draws the contents in, and forms an intracellular vesicle called an endosome. This vesicle travels through ...

By contrast, the bulk of endocytosis is often viewed as a constitutive process that ensures the continuous recycling of membrane components. In a recent paper (Mol. Cell 7, 421–432; 2001 ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...

To achieve this, it needs to induce the transport machinery of the cell to incorporate it into the host—otherwise known as ...

leading to the clustering of this protein and relocating it to cell membrane structures called lipid raft domains. This relocation ultimately triggers lipid raft-mediated endocytosis, leading to ...

These growth cues are received at the cell surface and are trafficked into the cell via a network of membrane-bound compartments called endosomes. However, we still do not understand the identity of ...

Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed—for instance in case ...

In secretory cells such as gonadotropes, the cytoplasmic face of the plasma membrane is associated with a dense meshwork of actin filaments (termed cortical actin) and actin binding proteins that play ...

membrane structure and function, cell adhesion, intercellular communication, signal transduction, chemotaxis, receptor-medicated endocytosis and intracellular trafficking. Mechanisms underlying ...

membrane structure and function, cell adhesion, intercellular communication, signal transduction, chemotaxis, receptor-mediated endocytosis and intracellular trafficking. Mechanisms underlying ...

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells ...

These membranes, composed of flexible lipid bilayers, can reshape and remodel themselves during processes like cell movement, division, and molecular trafficking. Until now, it was commonly assumed ...