It is unclear whether these beneficial effects are due solely to aldosterone blockade, as MR has a similar affinity for cortisol. We examined the relationships between plasma and urinary steroid ...

Both cortisol and aldosterone are potent activators of renal MCRs. In vitro, cortisol is a tenfold more potent activator of the MCR than aldosterone. In the kidney, 11β-hydroxysteroid ...

These are excessive adrenocortical secretion of aldosterone, Cortisol or mineralocorticoids that are not secreted in large amounts under normal conditions — for example, corticosterone (compound ...

Cortisol is a steroid hormone that regulates ... to take a hormone medication called fludrocortisone to replace the aldosterone their adrenal glands are no longer producing. This medication ...

Adrenal glands can also be impaired if there is a disorder in the pituitary gland, as it signals the adrenals to make certain ...

Addison's disease occurs when the adrenal glands do not produce enough hormones due to either the adrenal cortex not producing enough cortisol and aldosterone or when both adrenal glands have been ...

Spruce Biosciences, Inc. (NASDAQ:SPRB) revealed topline results from its CAHmelia-204 study of tildacerfont in adult CAH and ...