Cancer-like mutations in healthy cells point to genetic origins of breast cancer
BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early ...
The Harvard Crimson8h
HMS Study Reveals How Mutation Can Accelerate Breast Cancer Progression
A new study led by Harvard Medical School researchers shed new light on how even a single defective copy of the ...
Study reveals RNA's unknown role in DNA damage repair
A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role ...
Using CRISPR to decipher whether gene variants lead to cancer
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the ...
WebMD24d
EGFR Mutations in NSCLC: What Does It Mean?
When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing cancer. There are many types of EGFR mutations. The EGFR protein lives in the cell membrane with ...
News Medical8d
Scientists map cancer mutations in EGFR gene, revealing drug resistance paths
to study their effects on cancer progression and drug resistance. They found both previously known and novel mutations significantly linked to EGFR activation and drug response, demonstrating the ...
Medical Xpress29d
New AI tool predicts protein-protein interaction mutations in hundreds of diseases
The team also demonstrated that their model's protein-protein interaction mutations can predict: Survival rates and prognoses for various cancer types, including sarcoma, a rare but potentially ...
GEN8d
Combining Base and Prime Editing to Decipher Which Gene Variants Lead to Cancer
Researchers at ETH Zurich combined two CRISPR-Cas methods to decipher how mutations in a cell’s genome affect its function.
News Medical on MSN9d
Study sheds light on how BRCA1 gene mutations fuel breast cancer
A new study in mice explains how even a single faulty copy of the BRCA1 gene can fuel tumor growth. The findings suggest the dominant “two-hit” hypothesis of cancer development may not tell the full ...