Moss Point is a city in Jackson County, Mississippi, United States. The population was 12,147 in 2020, a decline from the figure of 13,704 in …Moss Point is a city in Jackson County, Mississippi, United States. The population was 12,147 in 2020, a decline from the figure of 13,704 in 2010. The Moss Point Historic District and several individual buildings are listed on the National Register of Historic Places' Jackson County listings.