Lonoke County is a county located in the Central Arkansas region of the U.S. state of Arkansas. As of the 2020 census, the population was 74,015, making it the 10th-most populous of Arkansas's 75 counties. The county seat is Lonoke and largest city is Cabot. Included in the Central Arkansas metropolitan area, with Little Rock as the principal city, it is an alcoho…Lonoke County is a county located in the Central Arkansas region of the U.S. state of Arkansas. As of the 2020 census, the population was 74,015, making it the 10th-most populous of Arkansas's 75 counties. The county seat is Lonoke and largest city is Cabot. Included in the Central Arkansas metropolitan area, with Little Rock as the principal city, it is an alcohol prohibition or dry county.