Santa Cruz is the largest city and the county seat of Santa Cruz County, in Northern California. As of the 2020 census, the city population was 6…Santa Cruz is the largest city and the county seat of Santa Cruz County, in Northern California. As of the 2020 census, the city population was 62,956. Situated on the northern edge of Monterey Bay, Santa Cruz is a popular tourist destination, owing to its beaches, surf culture, and historic landmarks.
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