Santo Domingo, once known as Santo Domingo de Guzmán, known as Ciudad Trujillo between 1936 and 1961, is the capital and largest cit…Santo Domingo, once known as Santo Domingo de Guzmán, known as Ciudad Trujillo between 1936 and 1961, is the capital and largest city of the Dominican Republic and the largest metropolitan area in the Caribbean by population. As of 2022, the city and immediate surrounding area had a population of 1,029,110 while the total population is 3,798,699 when including Greater Santo Domingo. The city is coterminous with the boundaries of the Distrito Nacional, itself bordered on three sides by Santo Domingo Province.
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