Ladispoli is a comune in the Metropolitan City of Rome, in the Italian region of Lazio. It lies about 35 kilometres west of Rome, on the Mediā¦Ladispoli is a comune in the Metropolitan City of Rome, in the Italian region of Lazio. It lies about 35 kilometres west of Rome, on the Mediterranean Sea. Modern Ladispoli includes the site of the ancient Alsium at nearby Palo Laziale, the port of the Etruscan city of Cerveteri and later a Roman colony cited by Cicero.