Alcamo is the fourth-largest town and commune of the Province of Trapani, Sicily, with a population of 44.925 inhabitants. It is on the bo…Alcamo is the fourth-largest town and commune of the Province of Trapani, Sicily, with a population of 44.925 inhabitants. It is on the borderline with the Metropolitan City of Palermo at a distance of about 50 kilometres from Palermo and Trapani.