Sezela is a small town on the mouth of iSezela River in KwaZulu-Natal, South Africa. The town is 78.7 km south of Durban. It is notable for its large sugar mill. The river and the town are named after a crocodile. In 1828, the Zulu king, Shaka, hunted down a man-eating crocodile here. The crocodile was called iSezela meaning the one who finds by smell, for it was said that the crocodile hunted like a wild dog following a trail.